By H Rodolfo Juliani; James E Simon; Chi-Tang Ho
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The hypotensive effects might be from reduction of endothelium-synthesised nitric oxide concentration (15). Anti-Mycobacterial Activity A few South African medicinal plants were tested for anti-mycobacterial activity of which Marula was included. Marula did not show good activity with the bark extracts with a MIC greater than 100 µg/ml and therefore showed no activity as this was the highest concentration tested (22). Anti-Malarial Activity Bark decoctions are traditionally used as a prophylactic and cure for malaria (23).
West African pepper has been reported to possess significant antioxidant properties (11). The antioxidant activity was partially ascribed to the presence of phenolic amides (93). The oil and oleoresin was reported to have good flavoring and antioxidant properties in pork samples (94). The antioxidant activity of the extracts has been characterized by a great superoxide radical (11, 92), high hydroxyl radical scavenging activity (95). The use of P. guineense as antioxidant is a promising alternative to the use of synthetic antioxidants, it could play a role in the modulation of free radical induced disorders (11), possess potential health benefits by inhibiting lipid peroxidation, justifies the traditional uses in medicine, and potential use as a value-added ingredient for stabilizing food matrixes against lipid peroxidation reactions (96).