By Giuseppe Barbaro, Franck Boccara, Paul Skolnik, Giorgio Barbarini
This booklet makes a speciality of a number of the new scientific and organic insights with regards to HIV-associated metabolic and cardiovascular problems within the HAART period. The advent of hugely energetic antiretroviral remedy (HAART) has altered cardiovascular manifestations in HIV. at the one hand, HAART has considerably enhanced the standard of lifetime of HIV-infected sufferers. nevertheless, the early information have raised a few issues, developing an interesting medical surroundings.
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Extra resources for Cardiovascular Disease in AIDS, 2nd Edition
We can conclude that for European studies, the prevalence of MetS is increased in HIVinfected patients compared to the general population. Prevalence According to IDF definition Generally, the prevalence is lower when using this definition because of the necessary criteria of the abdominal perimeter. This element is uncommon in HIV-infected patients with a lipodystrophic syndrome. Samaras et al. , in an international cohort, reported a near similarly prevalence of 18% (ATP III-NCEP) and 14% (IDF) according to the two definitions.
J AIDS 30:471–477 Coplan PM, Nikas A, Japour A et al (2003) Incidence of myocardial infarction in randomized trials of protease inhibitor-based antiretroviral therapy: an analysis of four different protease inhibitors. AIDS Res Hum Retroviruses 19:449–455 Mary-Krause M, Cotte L, Simon A et al and the Clinical Epidemiology Group from the French Hospital Database (2003) Increased risk of my- 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. ocardial infarction with duration of protease inhibitor therapy in HIV-infected men.
30. 31. 32. 33. 34. 35. 36. 37. tric oxide synthase influences the clinical course of human immunodeficiency virus-associated cardiomyopathy. Circulation 100:933–939 Pugliese A, Isnardi D, Saini A et al (2000) Impact of highly active antiretroviral therapy in HIV-positive patients with cardiac involvement. J Infect 40:282–284 Bijl M, Dieleman JP, Simoons M, Van Der Ende ME (2001) Low prevalence of cardiac abnormalities in an HIV-seropositive population on antiretroviral combination therapy. J AIDS 27:318–320 Nzuobontane D, Blackett KN, Kuaban C (2002) Cardiac involvement in HIV-infected people in Yaounde, Cameroon.