Clinical Guide to Primary Angioplasty by Stephen Brecker, Martin Rothman

By Stephen Brecker, Martin Rothman

Primary angioplasty is a life-saving, minimally invasive emergency method more and more utilized in the remedy of acute myocardial infarction. because the strategy extra proves its effectiveness, it's important that every one cardiologists have a finished knowing of the foremost concerns surrounding basic angioplasty. This easy-to-use, clinically concentrated textual content is a necessary reference for these hoping to accomplish this realizing. A important academic instrument, this article totally explores the very important recommendations of basic angioplasty.

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Although the evidence supporting the routine use of aspirin is overwhelming, this agent affects platelet function via only one mechanism (cyclooxygenase inhibition). The beneficial effects of aspirin may thus be supplemented by administration of agents that act via different mechanisms. The intravenous form of aspirin available in many countries is more rapidly effective (no delay due to intestinal absorption) and easier to use in emergency, and particularly useful in patients who are agitated, unconscious, in shock or have nausea.

86. Lincoff AM, Califf RM, Van de Werf F, et al; Global Use of Strategies to Open Coronary Arteries Investigators (GUSTO). Mortality at 1 year with combination platelet glycoprotein IIb/IIIa inhibition and reduced-dose fibrinolytic therapy vs conventional fibrinolytic therapy for acute myocardial infarction: GUSTO V randomized trial. JAMA 2002; 288:2130–2135. 87. Arhan A, Ecollan P, Madonna-Py B, et al. Assessment of early administration of abciximab in acute ST-segment elevation myocardial infarction in the emergency room.

80. White HD, Braunwald E, Murphy SA, et al. Enoxaparin vs. unfractionated heparin with fibrinolysis for ST-elevation myocardial infarction in elderly and younger patients: results from ExTRACT-TIMI 25. Eur Heart J 2007; 28:1066–1071. 81. Singh S, Molnar J, Arora R. Efficacy and safety of bivalirudin versus heparins in reduction of cardiac outcomes in acute coronary syndrome and percutaneous coronary interventions. J Cardiovasc Pharmacol Ther 2007; 12:283–291. 82. Stone GW, McLaurin BT, Cox DA, et al.

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